Professor Simon Gibbons
Professor Simon Gibbons

Selected research

Arunotayanun W, Dalley JW, Huang XP, Setola V, Treble R, Iversen J, Roth BL, Gibbons S (2013) An Analysis of the Synthetic Tryptamines AMT and 5-MeO-DALT: Emerging “Novel Psychoactive Drugs” Bioorganic Medicinal Chemistry Letters 23:3411-3415.


Shiu WK, Malkinson JP, Rahman MM, Curry J, Stapleton P, Gunaratnam M, Neidle S, Gibbons S, et al. (2013). A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus. Int J Antimicrob Agents 42:513-518.

Echinacea plant

Gibbons S, Arunotayanum W (2012) Natural Product “Legal Highs”. Natural Product Reports 29:1304-1316.

Professor Simon Gibbons

Professor of Medicinal Phytochemistry and Head of the Department of Pharmaceutical and Biological Chemistry

Tel: 0207 753 5913


  • Head of Department of Pharmaceutical and Biological Chemistry
  • President of the Phytochemical Society of Europe
  • Member of the Home Office’ Advisory Council on the Misuse of Drugs (ACMD)
  • Chairman of the ACMDs Novel Psychoactive Substances Committee
  • Member of the Governing Council of the College of Medicine

Research interests

  • Antibacterial plant natural products
  • Natural product bacterial resistance modifying agents
  • The chemistry and pharmacology of novel psychoactive substances and drugs of abuse
  • Phytochemistry of Herbal drugs

Teaching interests

Current teaching on the MPharm

  • Natural Product Drug Discovery (2nd year)
  • Natural Product Poisons (2nd Year)
  • Therapeutic Uses of Plants, Anticancer Natural Products and Legal Highs (4th Year and MSc in Pharmacognosy)
  • Structure Elucidation (MSc in Pharmacognosy and MSc in Drug Discovery)

Current collaborations and partnerships

  • With Professor Laura Piddock (University of Birmingham) we are studying natural products that inhibit Gram-negative bacterial multidrug efflux, specifically proteins of the resistance nodulation division family such as AcrABTolC.
  • In collaboration with Professor Bryan Roth at the University of North Carolina, we are studying the chemistry and neuropharmacology of novel psychoactive substances, which are becoming prominent drugs of abuse. 
  • A long standing and highly fruitful collaboration is in place with Professor Glenn W Kaatz of Wayne State University to study efflux pump inhibitors against Staphylococcus aureus.


  • BSc Hons in Applied Chemistry, First Class, 1989, Kingston Polytechnic
  • PhD in Phytochemistry, Strathclyde University